Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogs
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چکیده
منابع مشابه
Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogs.
We hypothesized that chronic intermittent hypoxia (CIH) would induce a predisposition to apnea in response to induced hypocapnia. To test this, we used pressure support ventilation to quantify the difference in end-tidal partial pressure of CO(2) (Pet(CO(2))) between eupnea and the apneic threshold ("CO(2) reserve") as an index of the propensity for apnea and unstable breathing during sleep, bo...
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RATIONALE Obstructive sleep apnea, a condition leading to chronic intermittent hypoxia (CIH), is associated with hyperlipidemia, atherosclerosis, and a high cardiovascular risk. A causal link between obstructive sleep apnea and atherosclerosis has not been established. OBJECTIVES The objective of the present study was to examine whether CIH may induce atherosclerosis in C57BL/6J mice. METHO...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2007
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00735.2007